Elidel is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Elidel availability.
When there is a range of pricing, consumers should normally expect to pay the lower price. However, due to stock shortages and other unknown variables we cannot provide any guarantee. The free Drugs. Please note: This is a drug discount program, not an insurance plan. Elidel offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples.
Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office. Elidel Rx Access Program: More information please phone: Patient assistance programs PAPs are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines.
Eligibility requirements vary for each program. Looking to reduce costs at the pharmacy counter? Here are 10 ways to save money on prescription drugs. By clicking Subscribe, I agree to the Drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to receive email notifications whenever new articles are published. Elidel Manufacturer: Novartis Program Name: Novartis Income Limits family size of one — family size of two: Office - 30 days supply.
Many people are discouraged by the Elidel PAP application process, which requires patients and their doctors to fill out many forms and provide extensive documentation. Our partner company, Rx Access, can help you. Sometimes patients have unusual personal circumstances that do not fit normal eligibility guidelines, which means that the applicant must file a formal appeal to get into the Elidel PAP program.
Rx Access prepares all the Elidel application paperwork so you can successfully apply for Novartis's Elidel Prescription Assistance and any other PAP programs you might qualify for—all for a nominal monthly fee that starts only if and when you are accepted into the PAP program.
Rx Access makes the process of applying for and receiving the free Elidel you need simple, fast and frustration-free. If flares occurred, moderately potent topical corticosteroids were mandated. The primary efficacy endpoint was ranked flares at 6 months. Safety was monitored clinically, and a skin recall-antigen test was performed at study completion.
The mean age for both groups was approximately 8 years, and the majority of patients had moderate disease at baseline. The discontinuation rate was significantly higher in the control group than in the pimecrolimus group The main reason for the higher discontinuation rate in the control group was unsatisfactory therapeutic effect This resulted in a substantially higher mean number of study medication treatment days in the pimecrolimus group compared with the control group: Of those patients who completed 12 months on study, To assess early intervention with pimecrolimus combined with corticosteroid CS for major flares in patients with severe atopic dermatitis AD.
For major flares not controlled with study medication, a mid-potency CS cream replaced the evening study drug for up to 3 weeks. The percentage of subjects with no major flares was the main outcome measure. Pimecrolimus reduced the major flare incidence and prolonged flare-free intervals. Combination therapy with pimecrolimus used at half the recommended dose did not shorten the mean flare duration or alter the AE profile.
Pimecrolimus and topical corticosteroids TCS combination therapy may provide an alternative treatment for patients with severe atopic dermatitis AD , with faster clearance of disease flares, consequently reducing the duration of TCS treatment. The primary outcome measure was the frequency of clinically relevant pre-defined adverse events AEs associated with the topical use of corticosteroids in patients with severe AD. Erythematous rash was the only AE, occurring more frequently in the combination group, while there were no noticeable differences in the frequency of other AEs of clinical interest between treatment groups.
Efficacy variables were comparable between the two groups. Chronic hand dermatitis is common and difficult to treat. Primary efficacy was 5-point Investigators' Global Assessment of prospectively selected 'target hand' as treatment success Investigators' Global Assessment 0 or 1 and treatment failure. Pruritus relief was also assessed.
Following double-blind phase treatment, target hand treatment success was achieved in The proportion of patients experiencing pruritus relief was significantly higher in the pimecrolimus group compared to the vehicle group at all time points throughout the double-blind phase. The groups were comparable with respect to treating disease signs. Pruritus relief, however, was significantly greater in the pimecrolimus group. Copyright S. Karger AG, Basel. This multicenter trial enrolled outpatients aged 2 to 17 years, with mild-to-severe atopic dermatitis.
The patients were initially treated with twice-daily topical pimecrolimus until complete clearance or for up to 6 weeks open-label period. The relapse rate was lower in the twice-daily dose group 9. Colonization with Staphylococcus aureus in atopic dermatitis AD is often associated with worsening of clinical symptoms. Staphylococcus aureus produces superantigens that contribute to cutaneous inflammation and corticosteroid CS resistance.
To investigate the relationship between CS insensitivity, S. This was a randomized, double-blind, vehicle-controlled, multicentre, parallel-group study. Seventy-three patients with AD, aged years, who had a documented clinical insensitivity to topical CS, were recruited. The primary efficacy parameters combined laboratory including S.
An increase in S. The presence of superantigens correlated with this worsening. During the 6-week double-blind phase, disease improvement in the pimecrolimus cream group was demonstrated by decreasing EASI scores compared with vehicle. Mean EASI scores for the head and neck showed greater improvement in the pimecrolimus cream group than in the vehicle group at all observed time points.
In a cohort of patients with clinical insensitivity to CS there was a significant positive correlation between S. Pimecrolimus Topical. Pimecrolimus is used to control the symptoms of eczema atopic dermatitis; a skin disease that causes the Health plan budget impact analysis for pimecrolimus. Budget impact models are useful tools for managed care organizations to make drug formulary decisions.
Estimates of the percentage of patients seeking care, treatment patterns, and quantities of medications dispensed for AD were measured using and medical and pharmacy records in a proprietary database for health plans distributed throughout the United States. Approximately 2. Costs for medications were assigned using the wholesale acquisition cost, and costs for physician visits were based on average Medicare reimbursement rates. Efficacy data from clinical trials were used to model the impact of pimecrolimus on subsequent physician visits. Sensitivity analyses were performed to evaluate the impact of varying the percentage of patients seeking care, practice patterns, medication quantities, percentage of pimecrolimus users, and levels of patient cost sharing.
The estimated percentage of health plan members seeking care for AD in was 3. In the year after its introduction, 5. The incremental increase in pharmacy benefit cost was 0. Based on sensitivity analyses, the incremental total cost PMPM after the introduction of pimecrolimus ranged from Formulary review of therapeutic alternatives for atopic dermatitis: Atopic dermatitis AD , often called eczema, is characterized by intense pruritus, erythema, dry skin, and inflammation. The condition is chronic and relapsing, and often occurs in patients with a family history of the atopic triad asthma, allergic rhinitis, and AD.
Use of topical steroids has been the mainstay of medical treatment for AD. Steroid-free treatments for AD, with a more favorable safety profile, have become available within the past 2 years. Tacrolimus ointment, a topical immunomodulator, became available in early and is indicated for moderate-to-severe AD. Pimecrolimus is indicated for mild-to-moderate AD. The objective of this article is to review the key characteristics that differentiate pimecrolimus from steroids and tacrolimus in the treatment of AD.
Using secondary resources, the clinical aspects and conventional treatment strategies for AD are reviewed as are the pivotal clinical studies with pimecrolimus and literature on quality of life and economic burden of disease for AD patients and families. Pimecrolimus is an effective, steroid-sparing therapy for mild-tomoderate AD. Early treatment prevents flares, the agent works quickly to reduce signs and symptoms of more advanced AD, and it is safe and appropriate for intermittent long-term therapy. Pimecrolimus has fewer side effects than topical steroids and a better side-effect profile than tacrolimus.
It can also be used as a first-line therapy. In studies with patients aged 2 to 17 years, it has been shown to be particularly effective in improving eczema of the face and neck, and its use may improve quality of life for many patients, especially children. The direct drug cost of pimecrolimus compares favorably with tacrolimus, but it is significantly more expensive than. Topical pimecrolimus versus betamethasone for oral lichen planus: Oral lichen plans OLP is a potentially malignant inflammatory mucocutaneous disease.
CD is an investigated surface marker for cancer stem-like cells CSCs that may be involved in tumor initiation in head and neck carcinomas. CD expression was detected in pre- and post-treatment immunostained sections. Pimecrolimus showed earlier clinical response and less recurrence rate compared with standard topical corticosteroid in symptomatic OLP lesions, and both treatment reduced CDpositive CSC population.
The study proved the benefits of topical pimecrolimus in early management of painful lesions of OLP and its ability to inhibit CSCs, suggesting a possible role in reducing risk of malignant transformation. Sports cream overdose. Sports creams are creams or ointments used to treat aches and pains. Sports cream overdose can occur if someone uses this Two ingredients in sports creams that can be poisonous are: Menthol Methyl salicylate. Addition of topical pimecrolimus to once-daily mid-potent steroid confers no short-term therapeutic benefit in the treatment of severe atopic dermatitis; a randomized controlled trial.
After 3 days of croton oil application, rats were treated with 0. Recently there has been an increase of interest to study the therapeutic potential of herbal plants as herbal care products. Two target areas of similar severity, size and location were assessed. Selection of fragrance for cosmetic cream containing olive oil. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
Two target areas of similar severity, size and location were assessed. Assessments included the modified Eczema Area and Severity Index scale primary variable , localized investigator global assessment scale and Patients' Self-Assessment of Disease Severity scale. A Multicentre Database Cohort Study. Despite the concerns about a potential increased risk of skin cancer and lymphoma with the use of topical tacrolimus and pimecrolimus , no population-based studies have given an overview of the use of these drugs in Europe.
To assess the use of topical tacrolimus and pimecrolimus in children and adults in Europe. We analysed users of topical tacrolimus and pimecrolimus starting from the date of first availability between and or start establishment of the prescription database in Sweden through The number of users increased rapidly after first availability, especially for topical tacrolimus.
Topical tacrolimus was more frequently used in all countries except Denmark. For both drugs, there was a decrease in users after in the Netherlands and Denmark and after in the UK, especially among children. This decrease was largest in Denmark. The decrease in the number of users was temporary for topical tacrolimus, while use remained relatively low for topical pimecrolimus.
The number of topical tacrolimus and pimecrolimus users increased rapidly after regulatory approval. A transient reduction in topical tacrolimus use and a persistent reduction in topical pimecrolimus use was seen after in the Netherlands and Denmark and after in the UK. Calcineurin inhibitors are potent inhibitors of T-cell-receptor mediated activation of the adaptive immune system. The effects of this class of drug on the innate immune response system are not known.
Keratinocytes are essential to innate immunity in skin and rely on toll-like receptors TLRs and antimicrobial peptides to appropriately recognize and respond to injury or microbes. In this study we examined the response of cultured human keratinocytes to pimecrolimus. Some of these responses were further enhanced by 1,25 vitamin D3. These observations uncover a previously unreported function for pimecrolimus in cutaneous innate host defense.
Pimecrolimus in atopic dermatitis: Consensus on safety and the need to allow use in infants. Atopic dermatitis AD is a distressing dermatological disease, which is highly prevalent during infancy, can persist into later life and requires long-term management with anti-inflammatory compounds.
The introduction of the topical calcineurin inhibitors TCIs , tacrolimus and pimecrolimus , more than 10 yr ago was a major breakthrough for the topical anti-inflammatory treatment of AD. The age restriction was emphasized in a boxed warning added by the FDA in January , which also highlights the lack of long-term safety data and the theoretical risk of skin malignancy and lymphoma.
Since then, pimecrolimus has been extensively investigated in short- and long-term studies including over infants pimecrolimus effectively treats AD in infants, with sustained improvement with long-term intermittent use. Unlike topical corticosteroids, long-term TCI use does not carry the risks of skin atrophy, impaired epidermal barrier function or enhanced percutaneous absorption, and so is suitable for AD treatment especially in sensitive skin areas.
Most importantly, the studies of pimecrolimus in infants provided no evidence for systemic immunosuppression, and a comprehensive body of evidence from clinical studies, post-marketing surveillance and epidemiological investigations does not support potential safety concerns.
In conclusion, the authors consider that the labelling restrictions regarding the use of pimecrolimus in infants are no longer justified and recommend that the validity of the boxed warning for TCIs should be reconsidered. Ice Cream Stick Math. Described is a teaching technique which uses the collection of ice cream sticks as a means of increasing awareness of quantity in a self-contained elementary special class for students with learning disabilities and mild mental retardation.
Butoconazole Vaginal Cream. This medication is sometimes prescribed for other uses; It is usually used daily at bedtime. Immunomodulation and safety of topical calcineurin inhibitors for the treatment of atopic dermatitis. Atopic dermatitis AD is a chronic or chronically relapsing inflammatory skin condition that primarily affects children. Topical corticosteroids have been the mainstay of treatment since the late s. Topical pimecrolimus is primarily used in children with mild and moderate AD, whereas tacrolimus is used preferentially in more severe cases. None of the topical calcineurin inhibitors have been associated with systemic immunosuppression-related malignancies known to occur following long-term sustained systemic immunosuppression with oral immunosuppressants e.
Preclinical and clinical data suggest a greater skin selectivity and larger safety margin for topical pimecrolimus. Ivermectin cream for rosacea. Rosacea is a chronic facial skin disease that mainly occurs in people aged over 30 years. For permission to use where not already granted under a licence please go to http: The physics of ice cream. Almost everybody likes ice cream , so it can provide an excellent vehicle for discussing and demonstrating a variety of physical phenomena, such as Newton's law of cooling, Boyle's law and the relationship between microstructure and macroscopic properties e.
Young's modulus. Furthermore, a demonstration of freezing point depression can be used to make ice cream in the classroom! Let's Make Metric Ice Cream. Describes a classroom activity which involved sixth grade students in a learning situation including making ice cream , safety procedures in a science laboratory, calibrating a thermometer, using metric units of volume and mass.
Terconazole Vaginal Cream , Vaginal Suppositories. It is usually used daily at bedtime for Ice cream , a popular product worldwide, is usually a milk-based product with other types of ingredients fruit, eggs, cocoa, dried fruit, additives, and others. Different materials are used to obtain the desired taste, texture, consistency, and appearance of the final product.
This study surveyed ice cream products available in Italy for heavy metals lead, cadmium, chromium, tin, and arsenic. The differences between artisanal and industrial ice cream were also investigated because of the importance in the Italian diet and the diffusion of this ready-to-eat food. Ice cream sampling was performed between October and February in the northeast of Italy.
A total of samples were randomly collected from different sources: Ten wooden sticks of industrial ice cream were analyzed in parallel to the ice cream. All samples were negative for arsenic and mercury. All positive lead samples were higher than the legal limit stated for milk 0. The heavy metals found in the wooden sticks were different from the corresponding ice cream , pointing out the lack of cross-contamination between the products. Considering the results and the amount of ice cream consumed during the year, contamination through ice cream is a low risk for the Italian population, even though there is need for further analysis.
To produce frozen cream eligible for official certification, the quality of To produce plastic cream eligible for official certification, the quality We Scream for Nano Ice Cream. There is a wide range of new products emerging from nanotechnology, and "nano ice cream " is an easy one that you can use to teach topics from surface area to volume applications.
In this activity, students learn how ice cream can be made smoother and creamier tasting through nanoscience. By using liquid nitrogen to cool the cream mixture, students…. The effect of ice- cream -scoop water on the hygiene of ice cream. An aerobic plate count around 10 6 c.
Unopened ice creams generally had counts around 10 3 4 c. Statistical analysis showed strong associations between indicator organisms and increased counts in ice cream in use. Herbal haemorrhoidal cream for haemorrhoids. Although hemorrhoids are one of the most common diseases in the world, the exact etiology underlying the development of hemorrhoids is not clear.
Many different ointments are currently used to treat hemorrhoids; however, there is little evidence of the efficacy of these treatments to support their use. The aim of this study was to compare different herbal creams used for the treatment of hemorrhoids. After 3 days of croton oil application, rats were treated with 0. Tissue and blood samples were collected for histological, immunohistochemical and biochemical studies.
Croton oil administration resulted in severe inflammation. The third group showed partial improvement in inflammation; however, the greatest degree of improvement was seen in the fourth group, and some recovered areas were observed. Myeloperoxidase immunoreactivity was found to be decreased in the third and fourth groups compared to the second group. In conclusion, croton oil causes inflammation in the anal area and results in hemorrhoids.
Treatment with our herbal hemorrhoid creams demonstrated anti-inflammatory and anti-oxidant effects in this model. Sour cream results from the souring, by lactic acid producing bacteria, of pasteurized cream Sour cream contains not less than 18 percent milkfat; except that when the food is characterized by the Pictured above, Goddard's astrobiology lab makes cookies and cream ice cream using liquid nitrogen at the Science Jamboree.
The event allowed the different departments at Goddard a chance to showcase their research and projects to other employees and summer interns. Rheological properties of ice cream mixes and frozen ice creams containing fat and fat replacers. In ice cream mixes, G' and G" exhibited a strong frequency dependence. Elastic properties of the ice cream mixes decreased as fat content decreased. Tan delta values indicated that fat replacers did not enhance the elastic properties of the ice cream mixes. In all frozen ice creams , G' and G" again showed a frequency dependence throughout the range tested 0.
The amount of fat in ice creams and the degree of fat destabilization affected the elasticity in the frozen product. Even though the ice creams did not have significant elastic properties, when compared as a group the samples with higher fat content had higher elastic properties. The addition of protein-based and carbohydrate-based fat replacers did not enhance the elastic properties of the ice creams but did increase the viscous properties.
Cream storage Ergonomics investigation of retail ice cream operations. A comprehensive ergonomics evaluation of retail ice cream shops, including field and laboratory data collection, was conducted using a human: The goal of the evaluation was to provide recommendations to enhance the health, safety, and productivity of shop employees. Active and passive surveillance and facility walk-throughs were used to guide the selection of analyses. A primary focus of the investigation was quantifying the task demands of scooping ice cream , which have not been documented in the literature.
This goal was accomplished through the use of a custom-designed instrumented ice cream scoop. Data were collected at an ice cream shop under typical conditions, while the laboratory experiment investigated task demands of ice cream scooping over a range of realistic temperatures. Manual materials handling task analyses and anthropometric evaluations comprised the majority of other analyses performed.
Recommendations are presented that are applicable to the operation of retail ice cream shops that serve hard i. Repellent action of neem cream against mosquitoes. Neem cream was used as mosquito repellent to provide protection against Aedes albopictus, Ae. The application of neem cream on exposed body parts 2. One or more of the clotting Each of the Cream concentrated latex for foam rubber products. The concentrated natural latex is an extremely valuable material.
It can be applied for many types of products, for example, foam rubber as pillow and mattress, elastic band, etc. Industrially, the concentrated natural latex can be prepared by centrifugation which requires an enormous expensive machine. From the eco-friendly products point of view, most of rubber entrepreneurs in the world try to develop a green rubber product.
So, the main objective of this study is to prepare the cream concentrated latex without any sophisticated machine. Thus, we work on a simple, cheap and green method that does not use any expensive machine but uses water-based chemical as sodium alginate to prepare the cream concentrated latex. The optimal amount of sodium alginate in the latex was studied. The main characteristics of the cream concentrated latex were tested by various technics, such as alkalinity, total solid content TSC , dry rubber content DRC , etc.
We found that there are no significant differences of results between fresh natural latex and cream concentrated latex, except for the TSC and DRC. Finally, we propose a model of natural rubber particle and sodium alginate to form the cream concentrated latex. Pityriasis Alba. A low potency topical corticosteroid may also be prescribed to decrease inflammation and reduce symptoms. Elidel , a nonsteroidal topical cream , can also reduce itching and redness associated Ice cream structural elements that affect melting rate and hardness. Statistical models were developed to reveal which structural elements of ice cream affect melting rate and hardness.
Ice creams were frozen in a batch freezer with three types of sweetener, three levels of the emulsifier polysorbate 80, and two different draw temperatures to produce ice creams with a range of microstructures. Ice cream mixes were analyzed for viscosity, and finished ice creams were analyzed for air cell and ice crystal size, overrun, and fat destabilization. The ice phase volume of each ice cream were calculated based on the freezing point of the mix.
Melting rate and hardness of each hardened ice cream was measured and correlated with the structural attributes by using analysis of variance and multiple linear regression. Fat destabilization, ice crystal size, and the consistency coefficient of the mix were found to affect the melting rate of ice cream , whereas hardness was influenced by ice phase volume, ice crystal size, overrun, fat destabilization, and the rheological properties of the mix.
Influence of full cream milk powder on the characteristics of sweet potato puree instant cream soup. A ready to use food such as instant cream soup become the most suitable choice for those who prefer being practical and also can be applied in any emergency situation such as areas affected by disaster. The adding of milk powder as the main ingredient in cream soup creates a complex bounding of fat and starch which complicates the rehydration process and affects other physical appearance. This research was aimed to find the proper concentration of full cream milk powder concentration to obtain the best characteristics of instant cream soup of dried sweet potato puree.
The method used in this research was randomized block design with 6 treatments Goat's milk ice cream. The impact of wood ice cream sticks' origin on the aroma of exposed ice cream mixes. The effect of volatile compounds in white birch sticks obtained from four different geographical locations on the aroma of ice cream mix was investigated. Sensory evaluation, specifically, a series of warmed-up paired comparisons was conducted on stick-exposed ice cream mixes to determine whether aroma differences in those mixes could be detected.
Batches of ice cream mix were exposed to the sticks and aged for 6 d at 4 degrees C and then assessed by the panelists by pairwise comparison. Findings suggest that differences in aroma of mixes that have been exposed to white birch sticks from four different geographical origins can be distinguished perceptually. Cream cheese with Goat's milk ice cream is the food prepared in the same manner Biofilm formation in an ice cream plant.
The sites of biofilm formation in an ice cream plant were investigated by sampling both the production line and the environment. Experiments were carried out twice within a day period. First, stainless steel coupons were fixed to surfaces adjacent to food contact surfaces, the floor drains and the doormat. They were taken for the analysis of biofilm at three different production stages. Then, biofilm forming bacteria were enumerated and also presence of Listeria monocytogenes was monitored.
Biofilm forming isolates were selected on the basis of colony morphology and Gram's reaction; Gram negative cocci and rod, Gram positive cocci and spore forming isolates were identified. Most of the biofilm formations were seen on the conveyor belt of a packaging machine 8 h after the beginning of the production, 6. Most of the Gram negative bacteria identified belong to Enterobacteriaceae family such as Proteus, Enterobacter, Citrobacter, Shigella, Escherichia, Edwardsiella. Gram positive microflora of the ice cream plant included Staphyloccus, Bacillus, Listeria and lactic acid bacteria such as Streptococcus, Leuconostoc or Pediococcus spp.
The results from this study highlighted the problems of spread of pathogens like Listeria and Shigella and spoilage bacteria. In the development of cleaning and disinfection procedures in ice cream plants, an awareness of these biofilm-forming bacteria is essential for the ice cream plants. Filtrates and Residues: Ice Cream: Delicious Chemistry. An experiment involving preparation of ice cream is conducted after students complete units on solutions, atomic structure, molecular architecture, and bonding.
The laboratory gives practical illustration of relation of physical properties to bond type and solution theory developed. Materials needed, procedures used, and questions asked are…. The areas to be treated are first cleared of exudate and the hair clipped Seborrheic dermatitis SD is an inflammatory skin disorder affecting the scalp, face, and trunk, however, there are controversies surrounding its treatment. In total, patients suffering from seborrheic dermatitis were studied. At the time of referral, and at 2 and 4 weeks after their first visit, the patients were examined by a dermatologist to check the improvement of clinical symptoms.
The mean age of patients was The highest level of satisfaction Production of functional probiotic, prebiotic, and synbiotic ice creams. In this work, 3 types of ice cream were produced: In addition to microbial counts, pH, acidity, and physical and functional properties of the ice creams were evaluated.
The experimental ice creams preserved the probiotic bacteria and had counts of viable lactic acid bacteria after frozen storage that met the minimum required to achieve probiotic effects. Moreover, most of the ice creams showed good nutritional and sensory properties, with the best results obtained with Lb.
Published by Elsevier Inc. All rights reserved. Ice cream structure modification by ice-binding proteins. Ice-binding proteins IBPs , also known as antifreeze proteins, were added to ice cream to investigate their effect on structure and texture.
*This offer is only valid for patients with commercial insurance. Eligible uninsured patients will pay more. This offer is not valid for any person eligible for. ELIDEL® (pimecrolimus) Cream 1% is a prescription topical cream (cream applied to the skin). It is available in g, g, and g tubes, from Valeant.
Ice recrystallization inhibition was assessed in the ice cream mixes using a novel accelerated microscope assay and the ice cream microstructure was studied using an ice crystal dispersion method. Larger individual ice crystals and no entrapment in control ice creams was observed. Based on these results a model of ice crystals aggregates formation in the presence of IBPs was proposed. Development of technology for manufacture of ragi ice cream. Ragi Finger millet improves the nutritional value of ice cream by enhancing the iron and fibre content.
In the next part of the study, ragi ice cream was prepared using 4 different flavours viz. Chocolate flavoured ragi ice cream was adjudged as best, followed by mango, caramel and vanilla ice cream. The iron and fibre content of chocolate flavoured ragi ice cream was found to be Incorporation of finger millet in ice cream resulted in reduction in the amount of stabilizer used and effectively functioned as fat replacer in ice cream. Dithranol in a cream preparation: In the search for the ideal dithranol cream preparation for short-contact treatment of psoriasis, we investigated the clinical efficacy, side effects and patient appreciation of two dithranol cream preparations cream A and B in a double-blind left-right comparing study.
Dithranol was dissolved at preparation in cream A and dispersed in cream B. Cream A is known to have a shelf life of 1 year, while cream B has a much shorter shelf life several months. Ten patients with chronic plaque-type psoriasis were treated during 7 weeks in a short-contact regimen. The clinical efficacy was monitored by scoring of erythema, induration, scaling and involved area PASI ; skin irritation was scored visually, and patient appreciation was evaluated by means of a multiple-choice questionnaire.
Dispersion of dithranol in a cream was associated with less irritation and less discoloration of the skin, and its efficacy was comparable with that of the cream in which the dithranol was dissolved. As the dispersed dithranol formulation is easier to be manufactured, its quality will be less depending on the pharmacist's experience and equipment, and so more reliable. Besides, it will be less expensive to prepare. We advise to use this formulation for short-contact treatment.
Investigation on the photostability of tretinoin in creams. In this investigation, the photodegradation of some tretinoin cream formulations was evaluated. Several oils were selected to prepare the cream formulations: A solubility study showed that tretinoin is best soluble in castor oil 0. Tretinoin seemed to be most stable in the olive oil cream , followed by the castor oil cream. However microscopic investigation revealed the presence of tretinoin crystals in the olive oil cream , while the other creams were free of it.
As a conclusion, one can say that the cream prepared with castor oil seems to be the most suitable one, in terms of solubility of tretinoin and in terms of photostability. Determination of ultraviolet filter activity on coconut oil cosmetic cream. A research on determination of ultraviolet UV filter activity of cosmetic cream with coconut oil as raw material has been done.
It was made also a cream with inorganic sunscreen TiO2 and organic sunscreen benzophenone-3 as a comparison. This means that, the cosmetic cream with coconut oil as raw material has an activity as UV-C filter. If this cream is expected to have an activity as a sunscreen, it must be added an inorganic or organic sunscreen or a mixture of both as an active materials. The effect of vaginal cream containing ginger in users of clotrimazole vaginal cream on vaginal candidiasis.
Vulvovaginal candidiasis is one of the most common infections of the genital tract in women that causes many complications. Therefore, we examined the clinical effect of ginger cream along with clotrimazole compared to vaginal clotrimazole alone in this study. This double-blind clinical trial was conducted on 67 women admitted to the Gynecology Clinic of Hajar Hospital with vaginal candidiasis.
The patients were divided randomly into two groups of 33 and 34 people.